Research Associate in Mass Spectrometry

The post-holder will lead the mass spectrometry-based metabolomics and lipidomics analysis of samples derived from alpha-synuclein filament preparations and related experimental systems. The aim is to discover, identify and quantify small molecules, lipids, or other non-proteinaceous components that may be associated with disease-relevant alpha-synuclein filament structures. You will develop and apply discovery metabolomics workflows, targeted mass spectrometry methods and robust chemometric approaches to compare sample classes, prioritise molecular features, assign molecular identities and support mechanistic interpretation.

Your responsibilities

• Develop, optimise and apply LC-MS-based discovery metabolomics and lipidomics workflows for complex biological samples.
• Analyse samples associated with alpha-synuclein filament preparations, including material derived from immunoprecipitation and filament-removal workflows.
Full-time Other

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